Mucuna Pruriens (Kapikacchu) Extract Capsule

Research

According to following research Mucuna extract due to its antioxidant property protects oxidative damage to erectile tissue and is useful in treating diabetes induced erectile dysfunction.

The Journal of Sexual Medicine

2011 Jul;8(7):1943-56. doi: 10.1111/j.1743-6109.2011.02221.x. Epub 2011 Mar 2.

Effect of Mucuna pruriens (Linn.) on oxidative stress-induced structural alteration of corpus cavernosum in streptozotocin-induced diabetic rat.

Suresh S1, Prakash S.

CONCLUSION:
The ethanolic extract of M. pruriens seed significantly recovered or protected erectile tissue from the oxidative stress-induced degeneration by its antioxidant potentials. These findings propound to serve mankind by the treatment of diabetes-induced erectile dysfunction.

http://www.ncbi.nlm.nih.gov/pubmed/21366877

Following research validates that Mucuna not only improves sperm quality of infertile men but also increased sexual drive and proper functioning of male reproductive system.

Evidance Based Complementary and Alternative Medicine.
Mar 2010; 7(1): 137–144.

Mucuna pruriens Reduces Stress and Improves the Quality of Semen in Infertile Men

Kamla Kant Shukla,1 Abbas Ali Mahdi,1 Mohammad Kaleem Ahmad,1 Shyam Pyari Jaiswar,2 Satya Narain Shankwar,3 and Sarvada Chandra Tiwari4

Conclusion:

On the basis of the afore-stated facts, it may be proposed that increased dopamine level in the brain may not only optimize the release of hormones, including testosterone, leading to increased sexual drive and improved performance, but it may also accomplish reduction of psychological stress. Moreover, treatment with Mucuna pruriens may also contribute to proper functioning of male genital system and facilitate sperm transport, contraction of seminal vesicles and inhibition of lipid peroxidation of spermatozoa.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816389/

Fertility and Sterility2009 Dec;92(6):1934-40. doi: 10.1016/j.fertnstert.2008.09.045. Epub 2008 Oct 29.

Mucuna pruriens improves male fertility by its action on the hypothalamus-pituitary-gonadal axis.

Shukla KK1, Mahdi AA, Ahmad MK, Shankhwar SN, Rajender S, Jaiswar SP.

Abstract
OBJECTIVE:
To understand the mechanism of action of Mucuna pruriens in the treatment of male infertility.
DESIGN:
Prospective study.
SETTING:
Departments of Biochemistry, Urology, and Obstetrics and Gynecology, C.S.M. Medical University, Lucknow, India.

PATIENT(S):
Seventy-five normal healthy fertile men (controls) and 75 men undergoing infertility screening.
INTERVENTION(S):
High-performance liquid chromatography assay for quantitation of dopa, adrenaline, and noradrenaline in seminal plasma and blood. Estimation by RIA of hormonal parameters in blood plasma, namely T, LH, FSH, and PRL.
MAIN OUTCOME MEASURE(S):
Before and after treatment, serum T, LH, FSH, PRL, dopamine, adrenaline, and noradrenaline in seminal and blood plasma were measured.
RESULT(S):
Decreased sperm count and motility were seen in infertile subjects. Serum T and LH levels, as well as seminal plasma and blood levels of dopamine, adrenaline, and noradrenaline were also decreased in all groups of infertile men. This was accompanied by significantly increased serum FSH and PRL levels in oligozoospermic subjects. Treatment with M. pruriens significantly improved T, LH, dopamine, adrenaline, and noradrenaline levels in infertile men and reduced levels of FSH and PRL. Sperm count and motility were significantly recovered in infertile men after treatment.
CONCLUSION(S):
Treatment with M. pruriens regulates steroidogenesis and improves semen quality in infertile men.

http://www.ncbi.nlm.nih.gov/pubmed/18973898

Mucuna seeds have been used in treating Parkinson’s disease known as “KAMPAVAT” in Ayurved for centuries, following British research validates its use in Parkinson’s disease.

Journal of Neurology, Neurosurgery and Psychiatry. 2004 Dec;75(12):1672-7.

Mucuna pruriens in Parkinson’s disease: a double blind clinical and pharmacological study.

Katzenschlager R1, Evans A, Manson A, Patsalos PN, Ratnaraj N, Watt H, Timmermann L, Van der Giessen R, Lees AJ.

National Hospital for Neurology and Neurosurgery, London, UK.

Abstract

BACKGROUND:

The seed powder of the leguminous plant, Mucuna pruriens has long been used in traditional Ayurvedic Indian medicine for diseases including parkinsonism. We have assessed the clinical effects and levodopa (L-dopa) pharmacokinetics following two different doses of mucuna preparation and compared them with standard L-dopa/carbidopa (LD/CD).

CONCLUSIONS:

The rapid onset of action and longer on time without concomitant increase in dyskinesias on mucuna seed powder formulation suggest that this natural source of L-dopa might possess advantages over conventional L-dopa preparations in the long term management of PD. Assessment of long term efficacy and tolerability in a randomised, controlled study is warranted.

http://www.ncbi.nlm.nih.gov/pubmed/15548480